KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC2
All Species:
27.27
Human Site:
T25
Identified Species:
37.5
UniProt:
P06493
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06493
NP_001777.1
297
34081
T25
V
Y
K
G
R
H
K
T
T
G
Q
V
V
A
M
Chimpanzee
Pan troglodytes
XP_001164618
264
30384
Rhesus Macaque
Macaca mulatta
XP_001095798
297
34077
T25
V
Y
K
G
R
H
K
T
T
G
Q
V
V
A
M
Dog
Lupus familis
XP_849450
297
34047
T25
V
Y
K
G
R
H
K
T
T
G
Q
V
V
A
M
Cat
Felis silvestris
Mouse
Mus musculus
P11440
297
34088
V25
V
Y
K
G
R
H
R
V
T
G
Q
I
V
A
M
Rat
Rattus norvegicus
P39951
297
34116
T25
V
Y
K
G
R
H
R
T
T
G
Q
I
V
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509674
303
34737
T25
V
Y
K
G
R
H
K
T
T
G
Q
V
V
A
M
Chicken
Gallus gallus
P13863
303
34670
T25
V
Y
K
G
R
H
K
T
T
G
Q
V
V
A
M
Frog
Xenopus laevis
P24033
302
34513
A25
V
Y
K
G
R
H
K
A
T
G
Q
V
V
A
M
Zebra Danio
Brachydanio rerio
NP_997729
302
34539
T25
V
Y
K
G
R
N
K
T
T
G
Q
V
V
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23572
297
34420
L25
V
Y
K
G
R
N
R
L
T
G
Q
I
V
A
M
Honey Bee
Apis mellifera
XP_393093
585
68394
K312
V
Y
K
G
K
H
K
K
T
G
E
I
V
A
M
Nematode Worm
Caenorhab. elegans
P34556
332
38277
R43
V
Y
K
G
K
N
R
R
T
N
A
M
V
A
M
Sea Urchin
Strong. purpuratus
XP_781415
301
34665
R25
V
Y
K
G
K
H
K
R
T
G
K
I
V
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
A25
V
Y
K
A
L
D
K
A
T
N
E
T
I
A
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
V25
V
Y
K
A
R
D
K
V
T
N
E
T
I
A
L
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
G33
L
D
L
R
P
G
Q
G
Q
R
V
V
A
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
99.3
98.6
N.A.
96.3
96.9
N.A.
95.3
90.4
84.7
81.4
N.A.
71.3
36.2
58.4
70.1
Protein Similarity:
100
88.8
99.6
99.6
N.A.
98.6
98.9
N.A.
96.6
94.3
93.3
91.7
N.A.
83.8
42.2
72.8
86.7
P-Site Identity:
100
0
100
100
N.A.
80
86.6
N.A.
100
100
93.3
93.3
N.A.
73.3
73.3
53.3
66.6
P-Site Similarity:
100
0
100
100
N.A.
93.3
100
N.A.
100
100
93.3
100
N.A.
93.3
93.3
80
93.3
Percent
Protein Identity:
N.A.
63.3
N.A.
64.9
59
N.A.
Protein Similarity:
N.A.
78.7
N.A.
79.4
76.5
N.A.
P-Site Identity:
N.A.
40
N.A.
46.6
6.6
N.A.
P-Site Similarity:
N.A.
60
N.A.
66.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
12
0
0
6
0
6
89
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
0
0
0
12
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
18
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
77
0
6
0
6
0
71
0
0
0
0
0
% G
% His:
0
0
0
0
0
59
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
30
12
0
0
% I
% Lys:
0
0
89
0
18
0
65
6
0
0
6
0
0
0
6
% K
% Leu:
6
0
6
0
6
0
0
6
0
0
0
0
0
6
18
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
71
% M
% Asn:
0
0
0
0
0
18
0
0
0
18
0
0
0
0
0
% N
% Pro:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
6
0
6
0
59
0
0
0
0
% Q
% Arg:
0
0
0
6
65
0
24
12
0
6
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
42
89
0
0
12
0
0
0
% T
% Val:
89
0
0
0
0
0
0
12
0
0
6
48
77
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
89
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _